Tofacitinib Synthesis - An Asymmetric Challenge
نویسندگان
چکیده
منابع مشابه
Tofacitinib
Tofacitinib (CP-690,550; CP-690550; CP690550), an orally active immunosuppressant, is being developed by Pfizer for the treatment of rheumatoid arthritis, inflammatory bowel disease, dry eyes, ankylosing spondylitis, psoriasis, psoriatic arthritis, and for the prevention of transplant rejection. Tofacitinib specifically inhibits Janus activated kinase 3 (JAK3), which has a pivotal role in cytok...
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ژورنال
عنوان ژورنال: European Journal of Organic Chemistry
سال: 2018
ISSN: 1434-193X
DOI: 10.1002/ejoc.201801180